Effects of hormone therapy on health related quality of life in postmenopausal women with CAD differed according to presence of menopausal symptoms.

Patients 2763 postmenopausal women < 80 years of age (mean age 67 y) with documented CAD (previous myocardial infarction [MI], > 50% luminal narrowing of a major vessel on angiography, or a previous coronary revascularisation procedure). Exclusion criteria were MI or revascularisation procedure in the previous 6 months, previous hysterectomy, contraindications to HT, HT in the previous 3 months, or life threatening illness. 2762 patients (99.9%) were included in the analysis; 2246 (81%) had HRQL data for all time points (baseline, 4 mo, 1 y, and 3 y).